Correlation between WT1 and chimeric gene expression levels in samples of BMT patients.

(A) Relationship between WT1 and AML1-MTG8. MRD levels in MRD⁺ samples obtained at different time points from 2 patients with AML1-MTG8 chimeric gene were analyzed by quantification of the gene expression levels of WT1 andAML1-MTG8. (B) Relationship between WT1 and minorbcr/abl. MRD levels in MRD⁺ samples from 2 patients with minor bcr-abl chimeric gene were analyzed as well. (C) The time courses of gene expression levels of WT1and AML1-MTG8 in a patient with AML. The expression level ofAML1/MTG8 in Kasumi-1 cells was defined as 1.0. The 2 MRD markers generally changed in parallel. ● indicates WT1gene expression levels; and ○, AML1-MTG8 gene expression levels.