Fig. 4.
Fig. 4. Global down-regulation of HOX gene expression in APL patient samples compared with normal bone marrow controls. / SMART-HOX was applied to cDNAs obtained from APL or normal bone marrow samples. Data presented are the mean CTvalues normalized for 18SrRNA and standard errors from triplicate experiments for (A) the HOXA cluster, (B) theHOXB cluster, (C) the HOXC cluster, and (D) theHOXD cluster genes (bone marrow, n = 3; APL, n = 16). ░ indicates bone marrow (BM); and ▪, APL.

Global down-regulation of HOX gene expression in APL patient samples compared with normal bone marrow controls.

SMART-HOX was applied to cDNAs obtained from APL or normal bone marrow samples. Data presented are the mean CTvalues normalized for 18SrRNA and standard errors from triplicate experiments for (A) the HOXA cluster, (B) theHOXB cluster, (C) the HOXC cluster, and (D) theHOXD cluster genes (bone marrow, n = 3; APL, n = 16). ░ indicates bone marrow (BM); and ▪, APL.

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