Normal skin structure and vascularization in adult PlGF-2 transgenic and wild-type mice.

Histologic analysis of the back skin of 8-week-old PlGF-2 transgenic mice (B,D) showed no major differences in the thickness and morphology of the epidermis and the dermis as compared with wild-type littermates (A,C). (A-B) Hematoxylin and eosin stains; (C-D) trichrome stains. CD31 stains demonstrated comparable vascularization of the skin of PlGF-2 transgenic mice (F) and of wild-type littermates (E). *Cutaneous vessels. Scale bars = 50 μm.