Fig. 3.
Effect of Pgp inhibitors on cell proliferation.
Cell proliferation of K562/DOX cells, under the effect of various concentrations of imatinib with or without 5 μg/mL verapamil (VP) or 1 μM PSC833, as assessed by MTS uptake. Results are expressed as the mean OD490 of quadruplicate cultures, which is directly proportional to the number of viable cells.