IgV_H mutation status in relation to CD38 expression and progressive or stable disease.

Data on 82 patients are plotted according to IgV_H sequence homology to germ line (x-axis), CD38 expression on CLL cells (y-axis), and status of the disease (○ indicates a patient with stable disease; ●, one with progressive disease). For clarity, 2 horizontal lines encompass the CLL patients with a CD38 bimodal expression profile and a vertical line divides mutated (< 98%) from unmutated (≥ 98%) CLL patients.