Fig. 3.
Morphogenic activity of AcSDKP.
(A) EA.hy926 cells were seeded on Matrigel and incubated for 2, 4, and 6 hours in the presence of 10−11 M and 10−9 M AcSDKP or 1 ng/mL bFGF. (B) EA.hy926 cells plated on Matrigel in the presence of various concentrations of AcSDKP or 1 ng/mL bFGF were cultured for 6 hours. Surface areas of the tubelike structure were evaluated by planimetry on at least 2 fields per well. Results are the means ± SEM of 5 independent experiments each performed in triplicate. *P < .05; **P < .01; ***P < .001.