Fig. 4.
![Fig. 4. Distortion of thymic, splenic, and lymph node architecture by anti-CD45 treatment. / Samples of thymus, spleen, and lymph node collected on days 1 and 30 from untreated mice and from mice treated with anti-CD45 (1 μg/g body weight) were stained with antibodies against CD5 T cells (in the thymus and lymph nodes) and against B220 B cells (in the spleen). The marker-positive cells were brown diaminobenzidine [DAB] against the blue nuclear stain hematoxylin. Severe distortion of normal thymic, splenic, and lymph node histology, first seen on day 1, persisted through day 30 (magnification × 10).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/6/10.1182_blood-2002-08-2379/4/h80633997004.jpeg?Expires=1735529848&Signature=f027zP6gBwhcekPppsBgBrhwFDL-lNPjDNVDSoahas9lN9TXtzW4PPaX3~SFRxYJt-4xtu8xrXpRNWumJ8Bo~NFTzIP065RI~14A7p7F3sIwSGBvHAfLjjkcrDCJHhGOGinRKv~nzOjw76pJrOm2YXO736WoY5KFMj3e0w2jVE46x-~kBSWhPM1LT45zZDoHvY8lyIVaW2dykySBDwbInPlSo3V-5w9gZLY9tvIcLfSX73l-eSRVbXMoQMdb7B8wz14GXTpielT8tfZR4M~mPh6hgxKkqqM11LpU-FZpB6WE3YYxB4yOnwOE6V00LAai6rejIKbpjEMLLm8ITSwElw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Distortion of thymic, splenic, and lymph node architecture by anti-CD45 treatment.
Samples of thymus, spleen, and lymph node collected on days 1 and 30 from untreated mice and from mice treated with anti-CD45 (1 μg/g body weight) were stained with antibodies against CD5 T cells (in the thymus and lymph nodes) and against B220 B cells (in the spleen). The marker-positive cells were brown diaminobenzidine [DAB] against the blue nuclear stain hematoxylin. Severe distortion of normal thymic, splenic, and lymph node histology, first seen on day 1, persisted through day 30 (magnification × 10).
