Fig. 3.
Effect of the S3483 compound on superoxide anion production in human PMNs and differentiated HL-60 cells.
Cells (1 × 106/mL) were pretreated (1 hour at 37°C) with solvent alone (10 μL/mL ethanol, ○), or with 50 (▿), 100 (▵), or 200 (■) μM S3484. Superoxide anion production was then induced by adding 1 μg/mL PMA. Values shown are means of 4 to 6 independent experiments; SEMs are shown for selected points only.