Fig. 4.
![Fig. 4. ITD mutations profoundly change gene expression profiles of myeloid progenitor cells. / (A) Scatter plot of the gene regulation values of IL-3 (ratio of IL-3 and medium [MED]) versus Flt3-ITD. (B) Scatter plot of the gene regulation values of ligand-activated Flt3-WT (ratio of FL and medium [MED]) versus Flt3-ITD. R depicts the correlation coefficient of logarithmically transformed expression ratios (Spearman nonparametric correlation).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/8/10.1182_blood-2002-06-1677/4/h80834133004.jpeg?Expires=1735834341&Signature=Tddzsr-tZQiUkcfnnQWj6s3Bknf-ncwePlLdpU4VjMIZqb~k1uwzi6K47fYBY7qrwBJ5xj~RB72W~2V8UNuZS~zCy0dLDmLIBzxa4rpQtgHdg808zH9qpoEIpHwV5e6Vveg9vaR23ASpI~gBERWQulJ~Wq~Ks~KRgUM8TJiD5iZQ-AP9J8H~OYZTeT2-bx0TDGCtcStFDNVvmxd9PKBiVYY88Gb5lzE~DeQHBdg2vARmYmVdOYTs2H~nUkipE2Dr-Uxi0jjzdQ2MnNH9~uw5qip1EdeRva9Sk27nXEkLgqQuJSLYSRcxL1G9wWjHA92FszvfPKvpixoHr9IT~eZU~w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
ITD mutations profoundly change gene expression profiles of myeloid progenitor cells.
(A) Scatter plot of the gene regulation values of IL-3 (ratio of IL-3 and medium [MED]) versus Flt3-ITD. (B) Scatter plot of the gene regulation values of ligand-activated Flt3-WT (ratio of FL and medium [MED]) versus Flt3-ITD. R depicts the correlation coefficient of logarithmically transformed expression ratios (Spearman nonparametric correlation).
