Fig. 7.
Addition of exogenous hemin reversed inhibition of hemoglobin synthesis induced by Bcl-XL antisense in DMSO-treated MEL cells.
745A/Neo and 745A/Bcl-XLAS cells were treated with DMSO (2%), hemin (100 μM), or the combined addition of DMSO (2%) and hemin (100 μM) for 5 days. Cellular hemoglobin production was determined by a spectrophotometric assay. Data represent the mean of triplicate cultures ± standard deviation.