DC generation from BM progenitor cells is impaired in TNF^−/− and TNFRp55^−/− mice but not in LTα^−/−, LTβ^−/−, or LTβR^−/− mice.

BM cells (1 × 10⁶ cells/mL) from several strains of KO mice were cultured with GM-CSF and IL-4 for 9 days. Cells were collected on day 9 and stained with FITC-conjugated anti–I-A^b mAb and PE-conjugated anti-CD11c mAb. The percent of events in each quadrant of dot plots is indicated. Data from 1 of 5 representative experiments are shown.