Effect of Tg A1-a on apoptosis and accumulation of T cells activated via the TCR.

Splenocytes were cultured for the indicated times in (A) control medium or (B-C) with αCD3 plus αCD28. (A-B) T-cell apoptosis was determined by staining with αThy1.2 and annexin. (C) Viable T-cell number was assessed by trypan blue exclusion. *P < .05 by Student t test.