Changes in serum levels of FDP(E) in rats subjected to renal ischemia/ reperfusion and effects of antithrombin (AT) and other materials on renal ischemia/reperfusion–induced increases in serum levels of FDP(E).

(A) Serum levels of FDP(E) were determined just before renal ischemia (Pre) and at indicated time points after reperfusion. (B) Serum levels of FDP(E) were determined 24 hours after reperfusion in rats subjected to renal ischemia/reperfusion (I/R). mAT indicates Trp49-modified AT. Data are expressed as mean ± SD values of 6 animals. Open circle indicates sham-operated group; filled circle, vehicle-treated group. *P < .05 versus sham-operated group; †P < .01 versus vehicle-treated group.