American Society of Hematology

Fig. 8.

$Fig. 8. Differential counts of bone marrow cells in suspension culture under G-CSF stimulation. / Bone marrow cells (5 × 105/mL) of normal mice, Tg mice expressing wild-type (WT) G-CSFR, and mutant receptors with 730 and 717 amino acid truncations, and their littermates (Lm) were incubated in suspension culture for a week in the presence of 20 ng/mL G-CSF. Others indicates erythroid cells, monocytes/macrophages, and megakaryocytes; Late Myeloid, mature neutrophils with a banded or segmented nucleus; and Early Myeloid, immature myeloid cell (myeloblasts to metamyelocytes). % indicates the percentage of each cell fraction in total bone marrow cells.$

Differential counts of bone marrow cells in suspension culture under G-CSF stimulation.

Bone marrow cells (5 × 10⁵/mL) of normal mice, Tg mice expressing wild-type (WT) G-CSFR, and mutant receptors with 730 and 717 amino acid truncations, and their littermates (Lm) were incubated in suspension culture for a week in the presence of 20 ng/mL G-CSF. Others indicates erythroid cells, monocytes/macrophages, and megakaryocytes; Late Myeloid, mature neutrophils with a banded or segmented nucleus; and Early Myeloid, immature myeloid cell (myeloblasts to metamyelocytes). % indicates the percentage of each cell fraction in total bone marrow cells.

This Feature Is Available To Subscribers Only