Fig. 4.
The effect of signal transduction inhibitors on IRBC cytoadherence.
Confluent HDMEC monolayers were pretreated with 25 μM PD098059 or 10 μM U0126 (n = 4) (A-B); 10 μM SB203580 or 10 μM SKF86002 (n = 3) (C-D); or a combination of U0126 and SB203580 (E-F) (n = 3). Monolayers were treated with all inhibitors for 30 minutes at 37°C. IRBCs were infused at 1 dyne/cm2. Values are presented as means ± SEM.
