Effect of Felic/CIP4 on cell migration.

(A) NIH3T3 cells expressing either Felic or CIP4 were compared with control cells in a Matrigel filter invasiveness assay. Data presented are the average ± standard error of the percentage of migrating cells. Results were statistically significant (*P < 0.05) using Student paired t test. (B) NIH3T3 cells transfected with empty vector (Control), Felic, or CIP4 were allowed to grow to confluence, then streaked horizontally with a sterile pipette tip. Microscopy with digital photography was performed at 24 and 48 hours after streaking. Original magnifications, × 100.