Fig. 1.
Effects of CTLA4-Ig and/or CsA on platelet Ag–induced T-cell proliferation in primary culture.
T cells (1 × 106/mL) from 36 patients with chronic AITP (▪) or 15 healthy control subjects (■) were cultured with acid-treated platelets and APCs for 7 days in the presence or the absence of CTLA4-Ig (10 μg/mL) and/or CsA (400 ng/mL). Proliferation was measured by [3H]thymidine incorporation and shown as mean ± SD cpm.