Fig. 3.
![Fig. 3. IL-2 reversed the T-cell tolerance to platelet Ags induced by CTLA4-Ig and/or CsA. / Following the same procedure for primary culture as that described in Figure 2, the T cells from 16 patients rendered tolerant to platelet Ags by CTLA4-Ig and/or CsA were rechallenged with platelet Ags and APCs in the presence (▪) or the absence (■) of IL-2 (10 U/mL) in the secondary culture. Proliferation was determined by [3H]thymidine incorporation on day 4 and shown as mean ± SD cpm.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/7/10.1182_blood-2002-06-1666/3/h80734058003.jpeg?Expires=1736047223&Signature=Xm5oFVQzYb~DF-~ttrpfeXn5lS4wcqP3wBTfAx-m6cfZuFuIRrva4WgKQHLU2iv96iH~tfv5nMItEZzZYLSVO3Niwv9f8CjSpsFAKb6imjnzfgHKyfeTtIbQOQVOcq8ldr48W7COqD~YZ4WpOkD6ZGtmEYp-kgN541wQvVxRf6vLlNZfbW3saJ2r6BMnHIB9mnz53w8IcnlkJsNH9EYky8KRc92B9UrUGqfbqUV71m1Q7sTjTvc~pWkydHiW2dXNVV2ov4RmTpjltMBmKfETyHZrZakpPql6cBEDzp6Pj94aafmSoT6t7AKu3Jz-MErmZYlH2GK4b5-0urZX90t7pg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IL-2 reversed the T-cell tolerance to platelet Ags induced by CTLA4-Ig and/or CsA.
Following the same procedure for primary culture as that described in Figure 2, the T cells from 16 patients rendered tolerant to platelet Ags by CTLA4-Ig and/or CsA were rechallenged with platelet Ags and APCs in the presence (▪) or the absence (■) of IL-2 (10 U/mL) in the secondary culture. Proliferation was determined by [3H]thymidine incorporation on day 4 and shown as mean ± SD cpm.
