Fig. 5.
Effects of CTLA4-Ig and/or CsA on IL-2 production on platelet Ag rechallenge.
Following the same procedure for first culture as that described in Figure 2, the T cells (1 × 106/mL) from 20 patients were rechallenged with the original Ags. Anti-Tac McAb (2 μg/mL) was added to the medium to block IL-2 consumption during the secondary culture. The supernatants were collected after 3 days, and IL-2 was measured by a bioassay on cytotoxic T-lymphocyte line (CTLL).
