IAP family mRNA expression. A quantitative RT-PCR analysis for survivin (A), cIAP1 (B), and XIAP (C) is shown in patients with acute, chronic, and smoldering ATL and in a healthy control (left), low PS and high PS (right). Each mRNA expression level was normalized on the basis of the GAPDH mRNA expression and expressed relative to the mRNA level in a healthy control. Boxes correspond to the interquartile range. Lines in the boxes represent median values. The vertical lines represent the 10th and 90th percentiles, and the circles represent the outliers. Differences were analyzed by Mann-Whitney's U test.