Figure 3.
Kinetics of antibody exposure after HIV-1 infection of iMDDCs. Virus was mixed with different concentrations of neutralizing mAb 2F5 or polyclonal IgG sample no. 11 for 1 hour prior to infection of iMDDCs (0); or antibody was added 1 hour (1), 2 hours (2), or 3 hours (3) after the infection. Percentages of HIV-1BaL–infected MDDCs in the presence of antibodies compared with control-infected cells were determined after 64 hours. Data are mean values of triplicate wells performed independently and repeated with iMDDCs from 3 different healthy donors.