Gene-expression patterns of CD34 cells after exposure to IFN-γ. Gene-expression profiles of 2 independent pools of CD34 cells derived from healthy controls were generated using Affymetrix HG-U95Av2 oligonucleotide GeneChips. Differential expression was defined as at least a 2-fold change in expression level in cells treated with IFN-γ compared with controls (Y or N, respectively). Values on the right indicate degree of upregulation and values on the left show the degree of downmodulation. “Absolute” expression levels (in arbitrary fluorescence units [AFUs]) are indicated using a color scale; red bars indicate high level of expression (> 1000 AFU); yellow bars, medium level of expression (200-1000 AFU); green bars, low level (20-200). ^* indicates genes previously known to be regulated by IFN-γ. GenBank number and gene name in red indicate altered expression in both CD34 and stroma cells; black letters indicate that the genes changed their expression only in one of the cell types studied.