Hyaluronan expression in small-intestine tissue. Tissue was collected from mice treated with TNFα without or with hyaluronidase (“H'ase”). HABP was used to stain specifically for HA. Blood vessels and leukocytes within vessels are indicated by arrows and arrowheads, respectively. Images represent × 400 magnification, and the negative control depicts the use of secondary antibody alone. One example from each group is shown.