Figure 6.
CD11c+CD11b+/- cells deliver T gondii into the brain. (A) Accumulation of CD11c+CD11b+/- and CD11c-CD11b+ cells in the brain of infected C57BL/6 mice previously engrafted with GFP+ bone marrow cells. (B) Number of parasites harbored by GFP+ brain cells from naive or infected chimeric mice. Values represent mean number plus SD for 3 to 5 mice per group. (C) Dot plots of CD11c+ and CD11b+ GFP+ cells naive or infected chimeric mouse brains. Brain GFP+ cells were isolated by FACS and stained. Numbers are the total CD11c+ or CD11b+ GFP+ cells per brain. Data are from a single experiment, representative of 2 separate experiments.