Figure 6.
GSH consumption and lipid peroxidation in bFGF-stimulated endothelial cells cultured on fibronectin or collagen and exposed to HKa. GSH consumption and lipid peroxidation were measured using protocols identical to those described in Figure 5. Panels A and B depict GSH consumption and lipid peroxidation, respectively, in cells cultured on fibronectin. Panels C and D depict GSH consumption and lipid peroxidation, respectively, in endothelial cells cultured on type I collagen. The differences in GSH consumption and phospholipid peroxidation were statistically significant only for cells cultured on fibronectin (P = .008 and .032, respectively). Error bars indicate standard deviation of triplicate points.