Figure 1.
Platelet numbers decrease following thermal injury. Groups of mice were either sham treated (n = 4, ○) or thermal injured (n = 8, •). At each time point tested, mice were killed, whole blood was removed by cardiac puncture, and platelet numbers were determined (A). Normal range for platelet numbers is 592 × 109/L (592 × 103/μL) to 2972 × 109/L (2972 × 103/μL), as outlined by the data analysis printout for the Hemavet 850 from Drew Scientific. Values below the dotted line represent thrombocytopenia. Hematocrits were determined from the same blood sample at each time point (B). The gray vertical bar represents the normal limits for hematocrit (.35-.45 [35.1%-45.4%]), as outlined by the data analysis printout for the Hemavet 850 from Drew Scientific. Data are representative of 2 independent experiments (mean ± SEM). Data were analyzed using the Mann-Whitney test. Differences were considered significant when *P < .05.