Analysis of VWF multimers of patients with sepsis-induced DIC. VWF multimers in the plasma of patients with sepsis-induced DIC with ADAMTS13 activity levels lower than 20% were analyzed by SDS-agarose gel electrophoresis, as described in “Patients, materials, and methods.” VWF multimer patterns of patients and healthy subjects (N) were analyzed simultaneously. *Representative unusually large multimers of VWF found in the plasma of patients with ADAMTS13 activity levels lower than 20%.