Platelet numbers remain depressed following thermal injury in platelet-deficient mice. C57BL/6J mice were treated as described in Figure 3. Anticoagulated whole blood was collected by cardiac puncture, and platelet numbers (A) and hematocrit (B) were determined at the times listed for groups CTL-Ig Sham (n = 16; open bars), CTL-Ig Burn (n = 22; dark gray bars), αPLT-Ig Sham (n = 16; light gray bars), and PLT-Ig Burn (n = 70; filled bars). Data (mean ± SEM) were analyzed using the Mann-Whitney test. *P < .05; **P < .01.