Figure 1.
Comparison of MRD assessment by consensus PCR with flow cytometry and quantitative PCR. MRD assessment by these techniques in samples from 3 representative patients (cases 1, 2, 3); ▪, MRD+ samples by consensus PCR; □, MRD– samples. MRD levels (y-axis) quantified by flow cytometry and quantitative PCR are shown in logarithmic scale. The majority of samples with MRD levels higher than 10–2 were positive by consensus PCR, whereas those with levels lower than 10–3 resulted in MRD– by consensus PCR. There was a zone represented by a light gray box, in which samples were either positive or negative independently of the MRD level.