Mutant RAS–containing MM cells demonstrate enhanced binding to fibronectin (FN) and stromal cells. (A) Adhesion to fibronectin (FN) was compared between WT, N-RAS, and K-RAS ANBL-6 cells, and results are presented as OD (570 nm) of crystal violet–stained cells, mean ± SD, n = 3. □ indicates adhesion to BSA, a nonspecific substrate; ▪, adhesion to FN. (B) WT, N-RAS, and K-RAS ANBL-6 cells were adhered to monolayers of the BMSC cell line KM102, and relative cell adhesion to BMSCs was quantified as OD of crystal violet–stained cells, mean ± SD, n = 3.