Figure 3.
Flow cytometric cell surface marker analysis of BM cells of a diseased mouse that received TEL2-BM transplants and a healthy control mouse that received MSCV-BM transplants. (A) Top row shows expression of the indicated cell surface markers (y-axis) versus GFP expression (x-axis) in MSCV-BM cells. The bottom row shows expression of these markers and GFP in TEL2-BM cells. TEL2-BM cells show increased percentages of cells expressing all of the markers, but most cells are positive for Mac1 and Gr1. The malignant cells in the spleen, liver, and peripheral blood expressed the same complement of cell surface markers (not shown).