TEL2 expression reduces the rate of apoptosis of BM cells cultured in vitro. UN-BM cells (top 2 panels) and retrovirus-transduced MSCV-BM cells (middle 2 panels) and TEL2-BM cells (bottom 2 panels) were inoculated in liquid culture in presence of myeloid growth factors. After 4 days of culture and staining with propidium iodide, cells were analyzed for GFP expression (left panels) and for annexin V expression (right panels) by FACS. The number of apoptotic cells in the TEL2-BM sample (bottom right quadrant of the dot plots) was half of that in the UN-BM and MSCV-BM samples. The same was true for the percentage of dead cells (top right quadrant of the dot plots).