In situ hybridization analysis of ADAMTS13 mRNA. Liver sections from Adamts13^+/+ (top panels) and Adamts13^–/– (bottom panels) mice were hybridized to the antisense (left panels) or sense (right panels) Adamts13 RNA probes. The hybridized sections were counterstained with Kernechtrot solution. Typical positive signals are indicated by arrows.