TFS in previously untreated patients. Probability of disease progression, as indicated by TFS. (A) TFS of patients with translocations (n = 11) and without translocations (n = 44) detected by metaphase analysis (P < .001). (B) TFS in patients with 13q deletion as the sole abnormality observed by FISH with (n = 7) and without (n = 23) additional translocations (P = .001).