Figure 4.
Histologic features of spleen of leukemic mice that received transplants under intermittent hypoxia. (A) In the same experiments as those described in Figure 2, splenocytes were collected onto slides by cytospin, stained by Wright Giemsa, and observed under a microscope (original magnification × 100/1.30 NA oil objective lens). (B-C) Histopathologic sections were stained with H&E (B, original magnification × 10/0.30 NA PH1 objective lens; C, original magnification × 100/1.30 NA oil objective lens). Arrowheads indicate mature myeloid cells with ring- (black) or horseshoe-shaped (blue) nuclei. Symbols i to v represent mice with the same treatment as in Figure 2.