Figure 6.
Figure 6. Photochemically injured intestinal vessel thrombosis. Distribution of occlusion time and mean (horizontal bars) upon injury induction in venules (top panel) and arterioles (bottom panel) of WT and Tsp1-null mice, without (Tsp1-/-) or after pretreatment with human TSP-1 or anti-ADAMTS13 IgGs for the indicated number of mice (m); thin parallel lines reflect the time to first massive thrombus formation in Tsp1-null mice; C indicates nontreated controls; +TSP-1, bolus of 80 μg/kg + infusion of 80 μg/kg/h; and +p-IgG, bolus of anti-ADAMTS13 IgG of 23 mg/kg + infusion of 23 mg/kg/h. P values were calculated via nonparametric Mann-Whitney test with 2-tailed P value.

Photochemically injured intestinal vessel thrombosis. Distribution of occlusion time and mean (horizontal bars) upon injury induction in venules (top panel) and arterioles (bottom panel) of WT and Tsp1-null mice, without (Tsp1-/-) or after pretreatment with human TSP-1 or anti-ADAMTS13 IgGs for the indicated number of mice (m); thin parallel lines reflect the time to first massive thrombus formation in Tsp1-null mice; C indicates nontreated controls; +TSP-1, bolus of 80 μg/kg + infusion of 80 μg/kg/h; and +p-IgG, bolus of anti-ADAMTS13 IgG of 23 mg/kg + infusion of 23 mg/kg/h. P values were calculated via nonparametric Mann-Whitney test with 2-tailed P value.

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