bGHTg mouse BM has large numbers of Sca-1⁺c-Kit⁺Lin^– cells, which engraft more rapidly than those from control mice. (A) Flow cytometry analysis of T (CD4, CD8) and B-cell (B220) populations and myeloid lineages (CD11b, Gr1) from bGHTg and control (wt) mouse PBLs. Values shown represent the percentage of positive cells. (B) Flow cytometry analysis of Sca-1⁺c-Kit⁺Lin^– BM cells from bGHTg and wt mice. (C) BrdU incorporation levels in BM cells from 3-month-old bGHTg and wt mice. Histograms correspond to representative animals (n = 6). (D) Flow cytometry analysis of mouse PBLs at 30 days after reconstitution with BM cells from bGHTg or wt mice. Data represent mean ± SD of 3 different experiments (n = 4 mice/assay).