Figure 4.
Examples of DNA methylation. (A) Pretreatment DNA methylation of MDR1, THBS2, and p57 using COBRA.20 Each lane represents a patient sample. UM indicates unmethylated; M, methylated; and C, methylated control. (B) Example of p15 methylation in a patient on days 0, 1, 5, 10, 21, and 28 of decitabine, VPA treatment. The 3 evaluated cytosines are enclosed in shaded squares. C indicates methylated cytosine; T, unmethylated site.
