Figure 5.
Receptor-modulated in vivo selection. Percentages of GFP+ red cells, platelets (plts), granulocytes (polys), B cells, and T cells in 5 mice that were given transplants of F36VFGFR1-transduced marrow cells (▴) and GFP+ red cells and platelets in 4 mice that were given transplants of F36VMpl-transduced marrow cells (•) prior to and following a 14-day course of AP20187. Vertical line depicts the start of CID treatment; ▵ depicts mean values of 4 control mice that were given transplants of F36VFGFR1-transduced marrow cells but not treated with CID. Error bars depict SEM.