Figure 4.
Figure 4. Transcriptional activation of AML1 by TPO. UT7-Mpl cells were transiently cotransfected with 400 ng pGL2-3 × AML1-TATALuc with or without 1μg pME18S-AML1wt. Cells were harvested after 20 hours of culture without (□) or with (▪) TPO, and luciferase assays were performed. Data represent mean ± SD of at least 3 independent experiments. *P < .05.

Transcriptional activation of AML1 by TPO. UT7-Mpl cells were transiently cotransfected with 400 ng pGL2-3 × AML1-TATALuc with or without 1μg pME18S-AML1wt. Cells were harvested after 20 hours of culture without (□) or with (▪) TPO, and luciferase assays were performed. Data represent mean ± SD of at least 3 independent experiments. *P < .05.

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