Figure 2.
5′ GR promoter transcript expression for in vitro prednisolone–sensitive and –resistant children with ALL. The mRNA expression of the 5′ GR promoter transcripts 1A1, 1A2, 1A3, 1B, and 1C as percentages of total GR promoter expression for 48 patients is depicted. The results are depicted as median (horizontal bars) and the 25th and 75th percentiles. Comparisons in expression levels of these 5 transcripts between GC-sensitive and -resistant patient samples were not significant.