Figure 1.
Tolerance in RIP-OVAhi mice. (A) Flow cytometric analysis of in vitro–restimulated splenocytes of inflova-infected B6 (left) or RIP-OVAhi mice (right). An IFNγ assay was performed 14 days after restimulation with 5 × 10–4 μg/mL OVA257-264 peptide (top) or PR366-374 peptide (bottom). (B) IFNγ production 14 days after restimulation with the OVA257-264 peptide (left) or PR366-374 peptide (right) of splenocytes from inflova-infected B6 (○) or RIP-OVAhi (•) mice. Each circle represents 1 mouse; bars, averages.