Figure 7.
Figure 7. DNA topoisomerase IIα gene expression and p21CIP1. The effect in HL60 cells of treatment for 3 days with vorinostat (Vor; 0.075-1 μM), VPA (0.25-3 mM), or IDA (1.5 nM) or the combination on p21CIP1 or DNA topoisomerase IIα mRNA expression was determined using real-time PCR assay. Numbers on the y-axis represent relative expression of delta CT. (A) p21CIP1. (B) DNA topoisomerase IIα. Error bars indicate standard deviation.

DNA topoisomerase IIα gene expression and p21CIP1. The effect in HL60 cells of treatment for 3 days with vorinostat (Vor; 0.075-1 μM), VPA (0.25-3 mM), or IDA (1.5 nM) or the combination on p21CIP1 or DNA topoisomerase IIα mRNA expression was determined using real-time PCR assay. Numbers on the y-axis represent relative expression of delta CT. (A) p21CIP1. (B) DNA topoisomerase IIα. Error bars indicate standard deviation.

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