Decrease in secreted MIP-1 α in response to FGFR3 inhibition. An ELISA for secreted MIP-1α demonstrated a reduction in secreted MIP-1α from both CHIR258 (500 nM)- and PD173074 (100 nM)-treated KMS11 cells (A) but not in inhibitor-resistant H929 cells (B). Error bars show standard deviation in replicate of 3 experiments.