Figure 7.
MIP-1 α expression in MM patients. (A) Gene-expression profiling of 231 newly diagnosed MM samples. The newly described TC classification is used to group patients.27 6 indicates t(6;14); 11, t(11;14); 4, t(4;14); m, t(14;16) or other maf “spiked” samples; and D1 and D2, Cyclin D1- and Cyclin D2-expressing samples, respectively. Samples were normalized to a median of 1 for examination of MIP-1α. (B) Ubiquitous expression of MIP-1α is noted except in patients with a t(11;14) or t(6;14) where its expression is statistically lower. The error bars show standard deviation. Horizontal bars indicate the mean.