Age-dependent examination of hematologic and iron parameters. Liver iron (μg iron/g wet tissue), serum iron (μM), and ferritin (ng/mL) were determined in control (Hepc1^+/+ and Hepc1^+/– mice) and Hepc1^–/– mice between 2 and 8 months of age. Statistical analysis was performed using Student t test (unpaired, 2-tailed). *P < .05; **P < .01; ***P < .001 as compared with sex- and age-matched animal; there were at least 5 animals in each group.