Figure 1.
Figure 1. Greater leukocyte accumulation in the peritoneum of Siat1ΔP1 and Siat1-null mice after intraperitoneal thioglycollate elicitation. Peritoneal lavage was recovered from wild-type C57BL/6 (WT), Siat1ΔP1 (ΔP1), and Siat1-null (null) animals in the absence of (0 hour; A), 5 hours after (B), and 1 day after (C) elicitation with 1 mL 4% wt/vol intraperitoneal thioglycollate. Viable cells were counted by hemocytometer after staining for trypan-blue exclusion. Age- and sex-matched mice were used. (A) n = 8WT, n = 8 ΔP1, and n = 4 null mice. (B) n = 8WT, n = 8 ΔP1 mice. (C) n = 8 WT, n = 8 ΔP1, and n = 4 null mice. *Mutant animal data points where statistically significant differences with corresponding WT have been reached. Statistical significance was noted as follows: P = .002, WT and ΔP1 (B); P = .002, WT and ΔP1 (C); and P = .001, WT and null (C). Error bars represent 1 standard deviation from the mean of each group.

Greater leukocyte accumulation in the peritoneum ofSiat1ΔP1 andSiat1-null mice after intraperitoneal thioglycollate elicitation. Peritoneal lavage was recovered from wild-type C57BL/6 (WT), Siat1ΔP1 (ΔP1), and Siat1-null (null) animals in the absence of (0 hour; A), 5 hours after (B), and 1 day after (C) elicitation with 1 mL 4% wt/vol intraperitoneal thioglycollate. Viable cells were counted by hemocytometer after staining for trypan-blue exclusion. Age- and sex-matched mice were used. (A) n = 8WT, n = 8 ΔP1, and n = 4 null mice. (B) n = 8WT, n = 8 ΔP1 mice. (C) n = 8 WT, n = 8 ΔP1, and n = 4 null mice. *Mutant animal data points where statistically significant differences with corresponding WT have been reached. Statistical significance was noted as follows: P = .002, WT and ΔP1 (B); P = .002, WT and ΔP1 (C); and P = .001, WT and null (C). Error bars represent 1 standard deviation from the mean of each group.

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