Figure 5.
Increased cytarabine resistance of clonogenic progenitors (CFU-Cs) following CDD gene transfer. Bone marrow harvested at the end of experiment C3 from 4 animals (2 each given transplants with CDD or control-transduced grafts) were exposed to increasing concentrations of cytarabine in clonogenic cultures. Drug resistance was assessed in triplicate cultures per animal and drug concentration.