Figure 3.
Effect of phagocytosis on actin polymerization and protein tyrosine phosphorylation in septic neutrophils. (A) Phagocytic index of neutrophils from controls (□) or patients with sepsis (▦), treated (+) or not (–) with CyB (15 μg/mL) or with genistein (Gen; 80 μM). Data are means ± SD. *P < .05 compared with controls (ANOVA followed by Bonferroni). Fluorescence microscopy (magnification: × 1000) for F-actin (B) and phoshotyrosine (C) of neutrophils from controls (i; □) and patients with sepsis (ii; ▦), after phagocytosis of opsonized zymosan, performed as described in “Patients, materials, and methods.”