Wound healing is delayed in hemophilia B mice. (A) The size of each wound in 2 dimensions was measured and the wound area in square millimeters calculated. The means ± SDs are plotted. The wound size in HB and WT mice differed significantly at days 1 to 10 (P < .05, indicated by × on the graph). (B) The percentage of wounds that were completely healed. Each point represents data from 18 to 23 mice.